botanical record · discovered
Seneca Snakeroot
Polygala senega
Seneca Snakeroot · Senega · Seneca snakeroot · senega snakeroot · senega-root · senegarot · sengaroot
At a glance
Origin / distribution: US(Amerindian), US(Appalachia), Turkey, US, US(VA), Japan*, JP
Cultural traditions: not documented
Recorded uses: Asthma, Bite(Snake), Diuretic, Emetic
Science studied: 1,5-ANHYDRO-(O-ALPHA-D-GALACTOPYRANOSYL-{1-2}-O-ALPHA-D-GALACTOPYRANOSYL-{1-2}), -D-GLUCITOL, ARABINOSYL-ALPHA-D-GALACTOSYL-D-GLUCOSE, P-COUMARIC-ACID
Research volume: 0 indexed records · volume only · methodology ↗
Legal status: Varies by jurisdiction; not assessed in this record.
Names and identity
Family: Polygalaceae
Scientific name: Polygala senega
Common names: Seneca Snakeroot, Senega, Seneca snakeroot, senega snakeroot, senega-root, senegarot, sengaroot
History
The source record documents this plant in Elsewhere, US(Amerindian), US(Appalachia), Turkey, US, US(VA), Japan*, JP.
It records these historical or traditional applications:
- Asthma
- Bite(Snake)
- Diuretic
- Emetic
- Expectorant
- Gout
- Hivess
- Medicine
show 8 more documented entries
- Pleurisy
- Poison
- Rheumatism
- Sudorific
- Alterative
- Bronchitis
- Cancer
- Tonic
This summary is limited to the cited source record.
Origins and distribution
- Elsewhere
- US(Amerindian)
- US(Appalachia)
- Turkey
- US
- US(VA)
- Japan*
- JP
Documented cultural uses
- Asthma
- Bite(Snake)
- Diuretic
- Emetic
- Expectorant
- Gout
- Hivess
- Medicine
- Pleurisy
- Poison
- Rheumatism
- Sudorific
show 4 more documented entries
- Alterative
- Bronchitis
- Cancer
- Tonic
Cultural record detail
These entries are transcribed from the cited ethnobotanical source; they do not represent current advice or a claim of efficacy.
- Asthma · Elsewhere · "
- Bite(Snake) · US(Amerindian) · "
- Bite(Snake) · US(Appalachia) · "
- Diuretic · Turkey · "
- Emetic · Turkey · "
- Expectorant · Elsewhere · "
- Expectorant · Turkey · "
- Gout · US · "
- Hivess · US · "
- Medicine · US(Appalachia) · "
- Pleurisy · US · "
- Poison · Elsewhere · "
- Rheumatism · US · "
- Sudorific · Turkey · "
- Alterative · Turkey · "
- Bronchitis · Elsewhere · "
- Cancer · US(VA) · "
- Tonic · Elsewhere · "
Contemporary uses
Contemporary practice is not documented separately in this record.
Scientific research
Indexed records indicate research activity; they do not establish efficacy or safety.
Indexed research records
- RETRACTION: Anticancer Potentials of Root Extract of <i>Polygala senega</i> and Its PLGA Nanoparticles-Encapsulated Form. · 2026 source ↗
- Preparation of Tenuifolin from <i>Polygala senega</i> L. Root Using a Hydrolytic Continuous Flow System under High-Temperature, High-Pressure Conditions. · 2021 source ↗
- Anti-angiogenic effect of triterpenoidal saponins from Polygala senega. · 2010 source ↗
Scientific compounds
Chemical presence is not evidence of clinical efficacy.
- 1,5-ANHYDRO-(O-ALPHA-D-GALACTOPYRANOSYL-{1-2}-O-ALPHA-D-GALACTOPYRANOSYL-{1-2})
- -D-GLUCITOL
- ARABINOSYL-ALPHA-D-GALACTOSYL-D-GLUCOSE
- P-COUMARIC-ACID
- 3,4-DIMETHOXYCINNAMIC-ACID
- FERULIC-ACID
- 2-O-ALPHA-D-GALACTOPYRANOSYL-1,5-ANHYDRO-D-GLUCITOL
- GALACTOSE
- HYDROXYSENEGIN
- MANNOSE
- P-METHOXY-CINNAMIC-ACID
- METHYL-SALICYLATE
- PECTIN
- POLYGALITOL
- RAFFINOSE
- SALICYLIC-ACID-METHYL-ESTER-PRIMVEROSIDE
show 24 more documented entries
- SENEGENIN
- SENEGENIC-ACID
- ALPHA-SPINASTEROL
- STACHYOSE
- TENUIFOLIN
- TENUIGENIN
- 3,4,5-TRIMETHOXYCINNAMIC-ACID
- XYLOSE
- GLUCOSE
- MANNINOTRIOSE
- PRESENEGIN
- RIBOSE
- SINAPIC-ACID
- ARABINOSE
- CYCLOSENEGIN
- FUCOSE
- 6-O-BETA-D-GLUCOPYRANOSYL-1,5-ANHYDRO-D-GLUCITOL
- POLYGALIC-ACID
- RHAMNOSE
- SENEGIN
- TENUIFOLIC-ACID
- VALERIANIC-ACID
- MONOTROPITOSIDE
- SAPONINS
Legality
No exact international trade listing was returned by the CITES checklist for this accepted name. Country-specific law is not assessed here.
Consult the CITES species checklist for current international and national requirements.
Reference images

Sources
Dr. Duke's Phytochemical and Ethnobotanical Databases · CC0
GBIF Backbone Taxonomy · CC BY 4.0
World Flora Online Plant List · WFO dataset terms; see release metadata
show claim source mapping
CC0 · Dr. Duke raw CSV archive
Contributions and revisions
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